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• Activity deltas table
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Motif ID: TFAP2{A,C}.p2

Z-value: 3.910

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr11_-_60819110	5.569		VWCE	von Willebrand factor C and EGF domains
chr11_-_60819273	4.993	NM_152718	VWCE	von Willebrand factor C and EGF domains
chr16_-_52877467	4.222		IRX3	iroquois homeobox 3
chr9_-_111300350	4.044	NM_001145368 NM_002829	PTPN3	protein tyrosine phosphatase, non-receptor type 3
chr19_+_39664706	4.028	NM_001080436	WTIP	Wilms tumor 1 interacting protein
chr16_+_52877009	3.950
chr10_+_101079099	3.743		CNNM1	cyclin M1
chr22_-_45311730	3.654	NM_014246	CELSR1	cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr5_+_129268352	3.600	NM_175856	CHSY3	chondroitin sulfate synthase 3
chr22_+_49459935	3.557	NM_001080420	SHANK3	SH3 and multiple ankyrin repeat domains 3
chr19_+_15079141	3.531	NM_033025	SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr5_-_159672060	3.491	NM_024565	CCNJL	cyclin J-like
chr6_+_41714171	3.439	NM_005586	MDFI	MyoD family inhibitor
chr22_-_32646325	3.427	NM_004737 NM_133642	LARGE	like-glycosyltransferase
chr9_+_115958051	3.415	NM_032888	COL27A1	collagen, type XXVII, alpha 1
chr14_+_92049396	3.384	NM_024832	RIN3	Ras and Rab interactor 3
chr5_+_176170041	3.322	NM_133369	UNC5A	unc-5 homolog A (C. elegans)
chr10_+_120779217	3.321	NM_199461	NANOS1	nanos homolog 1 (Drosophila)
chr17_+_56831951	3.318	NM_005994	TBX2	T-box 2
chr2_-_45090025	3.309	NM_016932	SIX2	SIX homeobox 2
chr17_+_56832255	3.272		TBX2	T-box 2
chr15_-_46724360	3.261		FBN1	fibrillin 1
chr16_-_66827449	3.246	NM_024939	ESRP2	epithelial splicing regulatory protein 2
chr16_-_52876390	3.207		IRX3	iroquois homeobox 3
chr10_-_76829857	3.177		ZNF503	zinc finger protein 503
chr9_-_37566248	3.149	NM_012166	FBXO10	F-box protein 10
chr12_+_119562737	3.145	NM_001033677	CABP1	calcium binding protein 1
chr16_-_71639670	3.120	NM_006885	ZFHX3	zinc finger homeobox 3
chr18_+_18969724	3.066	NM_001100619	CABLES1	Cdk5 and Abl enzyme substrate 1
chr17_-_19711580	3.019	NM_001142610 NM_014683	ULK2	unc-51-like kinase 2 (C. elegans)
chr2_+_159533329	2.944	NM_001145909 NM_033394	TANC1	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chrX_-_54538591	2.935		FGD1	FYVE, RhoGEF and PH domain containing 1
chr18_-_53621277	2.929	NM_005603	ATP8B1	ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr14_-_24588916	2.921	NM_014178	STXBP6	syntaxin binding protein 6 (amisyn)
chr7_-_22363036	2.858	NM_012294	RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5
chr15_+_49421004	2.807	NM_181789	GLDN	gliomedin
chr16_-_49742651	2.733	NM_002968	SALL1	sal-like 1 (Drosophila)
chr5_-_16670085	2.733	NM_001034850	FAM134B	family with sequence similarity 134, member B
chr2_+_236068029	2.732		AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr17_+_62391216	2.725	NM_014405	CACNG4	calcium channel, voltage-dependent, gamma subunit 4
chr10_-_123347493	2.717	NM_000141 NM_001144917 NM_001144918 NM_001144919 NM_022970	FGFR2	fibroblast growth factor receptor 2
chr14_-_93324518	2.633	NM_178013	PRIMA1	proline rich membrane anchor 1
chr16_-_52877868	2.595	NM_024336	IRX3	iroquois homeobox 3
chr2_+_39746525	2.593	NM_152390	TMEM178	transmembrane protein 178
chr7_-_27136876	2.583	NM_002141	HOXA4	homeobox A4
chr3_-_126257425	2.580	NM_020733	HEG1	HEG homolog 1 (zebrafish)
chr2_-_219633481	2.573	NM_002181	IHH	Indian hedgehog
chr22_-_39964001	2.558		CHADL	chondroadherin-like
chr11_-_407324	2.548	NM_001135053 NM_021805	SIGIRR	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr17_+_52026058	2.546	NM_005450	NOG	noggin
chr2_-_101370291	2.531		CREG2	cellular repressor of E1A-stimulated genes 2
chr2_-_42573980	2.522		KCNG3	potassium voltage-gated channel, subfamily G, member 3
chr9_+_115957537	2.499		COL27A1	collagen, type XXVII, alpha 1
chr3_+_50217692	2.491	NM_006841	SLC38A3	solute carrier family 38, member 3
chr11_+_10428799	2.447	NM_000480	AMPD3	adenosine monophosphate deaminase 3
chr7_-_27206249	2.403	NM_000522	HOXA13	homeobox A13
chr7_+_140420500	2.399	NM_001195278	LOC100131199	transmembrane protein 178-like
chr9_-_83493415	2.389	NM_005077	TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chrX_+_68641802	2.383	NM_015686	FAM155B	family with sequence similarity 155, member B
chr5_+_72957736	2.377	NM_001080479 NM_001177693	RGNEF	190 kDa guanine nucleotide exchange factor
chr15_+_64782468	2.362		SMAD6	SMAD family member 6
chr8_+_104582151	2.350	NM_001100117	RIMS2	regulating synaptic membrane exocytosis 2
chr1_+_226937732	2.342		RHOU	ras homolog gene family, member U
chrX_+_46318135	2.334	NM_019886	CHST7	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
chr18_-_22382497	2.334	NM_001142730	KCTD1	potassium channel tetramerisation domain containing 1
chr19_+_38377329	2.333	NM_002333	LRP3	low density lipoprotein receptor-related protein 3
chr20_+_6696744	2.331	NM_001200	BMP2	bone morphogenetic protein 2
chr3_+_44878380	2.329	NM_144638	TMEM42	transmembrane protein 42
chr18_-_22383066	2.325	NM_001136205	KCTD1	potassium channel tetramerisation domain containing 1
chr2_+_231610438	2.309	NM_001144994	C2orf72	chromosome 2 open reading frame 72
chr5_-_172594691	2.297	NM_001166175 NM_001166176 NM_004387	NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)
chr12_-_105056577	2.280		NUAK1	NUAK family, SNF1-like kinase, 1
chr7_+_288051	2.278	NM_020223	FAM20C	family with sequence similarity 20, member C
chr10_+_59942874	2.263	NM_001080512	BICC1	bicaudal C homolog 1 (Drosophila)
chr1_-_48235148	2.249	NM_001194986	LOC388630	UPF0632 protein A
chr16_+_22733307	2.232	NM_006043	HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr2_+_120820140	2.222	NM_002193	INHBB	inhibin, beta B
chr8_+_22492586	2.195		PDLIM2	PDZ and LIM domain 2 (mystique)
chr16_-_52877829	2.195		IRX3	iroquois homeobox 3
chr16_+_639278	2.146	NM_145294	WDR90	WD repeat domain 90
chr2_-_165186232	2.141		GRB14	growth factor receptor-bound protein 14
chr14_-_29466562	2.117	NM_002742	PRKD1	protein kinase D1
chr5_+_98132898	2.115	NM_001012761	RGMB	RGM domain family, member B
chr9_+_134027154	2.107	NM_032536	NTNG2	netrin G2
chr22_+_36531246	2.096		H1F0	H1 histone family, member 0
chr9_+_128416542	2.091	NM_001174146 NM_001174147 NM_002316	LMX1B	LIM homeobox transcription factor 1, beta
chr4_+_72271218	2.090	NM_001098484 NM_001134742	SLC4A4	solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr12_-_94708477	2.088		NTN4	netrin 4
chr3_+_114414064	2.084	NM_033254	BOC	Boc homolog (mouse)
chr6_+_1555679	2.071	NM_001453	FOXC1	forkhead box C1
chr1_+_64709063	2.066	NM_020925	CACHD1	cache domain containing 1
chr3_+_71885890	2.063	NM_018971	GPR27	G protein-coupled receptor 27
chr17_+_9489578	2.061	NM_153210	USP43	ubiquitin specific peptidase 43
chr2_-_224612177	2.037	NM_001136528 NM_006216	SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr2_+_176761552	2.035	NM_024501	HOXD1	homeobox D1
chr12_-_94708641	2.033	NM_021229	NTN4	netrin 4
chr17_+_8865547	2.031	NM_004822	NTN1	netrin 1
chr20_-_4177519	2.021	NM_000678	ADRA1D	adrenergic, alpha-1D-, receptor
chr7_+_94374862	2.019	NM_001166160 NM_017650	PPP1R9A	protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr8_-_38444982	2.006		FGFR1	fibroblast growth factor receptor 1
chr10_-_131652364	2.001		EBF3	early B-cell factor 3
chr2_+_36436873	1.995	NM_016441	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr2_+_36436316	1.993		CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr14_-_102593384	1.990	NM_006035	CDC42BPB	CDC42 binding protein kinase beta (DMPK-like)
chr14_-_59001603	1.987		GPR135	G protein-coupled receptor 135
chr14_+_32478209	1.983	NM_001164749 NM_001165893 NM_022123 NM_173159	NPAS3	neuronal PAS domain protein 3
chr10_+_122206455	1.975	NM_001030059	PPAPDC1A	phosphatidic acid phosphatase type 2 domain containing 1A
chr19_-_15172773	1.962	NM_000435	NOTCH3	notch 3
chr3_+_51403760	1.961	NM_013286	RBM15B	RNA binding motif protein 15B
chr17_-_64108331	1.961		FAM20A	family with sequence similarity 20, member A
chr17_-_59131194	1.952		LIMD2	LIM domain containing 2
chr9_+_94987032	1.951	NM_006648	WNK2	WNK lysine deficient protein kinase 2
chr17_-_71385651	1.940		TRIM47	tripartite motif containing 47
chr6_+_107917965	1.927	NM_018013	SOBP	sine oculis binding protein homolog (Drosophila)
chr12_+_108636569	1.922	NM_032829	C12orf34	chromosome 12 open reading frame 34
chr7_-_45927263	1.920	NM_000598 NM_001013398	IGFBP3	insulin-like growth factor binding protein 3
chr3_+_50167851	1.919	NM_004186	SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr8_+_30361485	1.918	NM_001008710 NM_001008711 NM_001008712 NM_006867	RBPMS	RNA binding protein with multiple splicing
chr20_+_8060762	1.918	NM_015192 NM_182734	PLCB1	phospholipase C, beta 1 (phosphoinositide-specific)
chr3_+_152286138	1.915		MED12L	mediator complex subunit 12-like
chr9_+_128128913	1.908	NM_001011703 NM_033446	FAM125B	family with sequence similarity 125, member B
chr20_-_30534848	1.903	NM_080616	C20orf112	chromosome 20 open reading frame 112
chr1_+_33494745	1.902	NM_152493	ZNF362	zinc finger protein 362
chr1_+_39319675	1.898	NM_012090	MACF1	microtubule-actin crosslinking factor 1
chr1_+_22909916	1.889	NM_004442 NM_017449	EPHB2	EPH receptor B2
chr6_+_53767747	1.886		LRRC1	leucine rich repeat containing 1
chr22_-_49315341	1.880	NM_001113755 NM_001953	TYMP	thymidine phosphorylase
chr8_-_8788149	1.877	NM_004225	MFHAS1	malignant fibrous histiocytoma amplified sequence 1
chr4_-_141896920	1.865	NM_015130	TBC1D9	TBC1 domain family, member 9 (with GRAM domain)
chr15_-_49174107	1.863		TNFAIP8L3	tumor necrosis factor, alpha-induced protein 8-like 3
chr4_+_108965167	1.863	NM_001136258	SGMS2	sphingomyelin synthase 2
chr18_-_44189625	1.860		ZBTB7C	zinc finger and BTB domain containing 7C
chr5_-_57791544	1.857	NM_006622	PLK2	polo-like kinase 2
chr16_+_67236699	1.847		CDH3	cadherin 3, type 1, P-cadherin (placental)
chr4_+_185064799	1.847		STOX2	storkhead box 2
chr20_-_30535045	1.838		C20orf112	chromosome 20 open reading frame 112
chr20_+_34206070	1.828	NM_012156	EPB41L1	erythrocyte membrane protein band 4.1-like 1
chr16_+_67236730	1.827		CDH3	cadherin 3, type 1, P-cadherin (placental)
chr12_-_105165805	1.818	NM_006825	CKAP4	cytoskeleton-associated protein 4
chr3_+_182912769	1.817		SOX2	SRY (sex determining region Y)-box 2
chr6_+_36206239	1.816	NM_002754	MAPK13	mitogen-activated protein kinase 13
chr2_+_42128521	1.813	NM_138370	PKDCC	protein kinase domain containing, cytoplasmic homolog (mouse)
chr1_+_2975590	1.807	NM_022114 NM_199454	PRDM16	PR domain containing 16
chr20_+_43875078	1.804	NM_181801	UBE2C	ubiquitin-conjugating enzyme E2C
chr17_-_6400470	1.802	NM_001165966 NM_031220	PITPNM3	PITPNM family member 3
chr7_+_27190688	1.801
chr1_-_62557559	1.797		KANK4	KN motif and ankyrin repeat domains 4
chr16_+_19087035	1.790	NM_016524	SYT17	synaptotagmin XVII
chr10_-_118491971	1.785	NM_025015	HSPA12A	heat shock 70kDa protein 12A
chr12_+_93066370	1.781	NM_005761	PLXNC1	plexin C1
chr1_-_94779727	1.777	NM_001178096 NM_001993	F3	coagulation factor III (thromboplastin, tissue factor)
chr14_-_94306104	1.760	NM_173849	GSC	goosecoid homeobox
chr2_-_42574587	1.757	NM_133329 NM_172344	KCNG3	potassium voltage-gated channel, subfamily G, member 3
chr20_-_45848043	1.754	NM_018837	SULF2	sulfatase 2
chrX_+_149282097	1.751	NM_001177465	MAMLD1	mastermind-like domain containing 1
chr7_+_288195	1.745		FAM20C	family with sequence similarity 20, member C
chr7_+_128615948	1.739	NM_005631	SMO	smoothened homolog (Drosophila)
chr2_+_149895274	1.738	NM_194317	LYPD6	LY6/PLAUR domain containing 6
chr14_+_69021149	1.734	NM_001161498	UPF0639	UPF0639 protein
chr3_+_185580554	1.730	NM_003741	CHRD	chordin
chr10_+_128583984	1.723	NM_001380	DOCK1	dedicator of cytokinesis 1
chr18_-_11138760	1.715	NM_022068	FAM38B	family with sequence similarity 38, member B
chr6_-_117193505	1.708	NM_001085480	FAM162B	family with sequence similarity 162, member B
chr2_-_135193011	1.708	NM_030923	TMEM163	transmembrane protein 163
chr15_+_82113813	1.698	NM_207517	ADAMTSL3	ADAMTS-like 3
chr20_+_4077466	1.694		SMOX	spermine oxidase
chr10_+_101078784	1.694	NM_020348	CNNM1	cyclin M1
chr18_+_46340400	1.692	NM_002747	MAPK4	mitogen-activated protein kinase 4
chr15_+_78483624	1.692	NM_014862	ARNT2	aryl-hydrocarbon receptor nuclear translocator 2
chr6_+_1556543	1.691		FOXC1	forkhead box C1
chr22_-_19122107	1.691	NM_153334 NM_182895	SCARF2	scavenger receptor class F, member 2
chr1_-_199635240	1.689	NM_005558	LAD1	ladinin 1
chr3_-_130807865	1.689	NM_015103	PLXND1	plexin D1
chr17_+_45993338	1.680	NM_018896 NM_198376 NM_198377 NM_198378 NM_198379 NM_198380 NM_198382 NM_198383 NM_198384 NM_198385 NM_198386 NM_198387 NM_198388 NM_198396 NM_198397	CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit
chr1_-_212791467	1.677		PTPN14	protein tyrosine phosphatase, non-receptor type 14
chr2_+_235525355	1.674	NM_014521	SH3BP4	SH3-domain binding protein 4
chr17_-_24917661	1.671		ABHD15	abhydrolase domain containing 15
chr14_+_68796621	1.667		GALNTL1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1
chr1_-_62557655	1.661	NM_181712	KANK4	KN motif and ankyrin repeat domains 4
chr12_-_15833617	1.659	NM_004447	EPS8	epidermal growth factor receptor pathway substrate 8
chr1_-_25128951	1.657		RUNX3	runt-related transcription factor 3
chr20_+_20296744	1.656	NM_002196	INSM1	insulinoma-associated 1
chr15_-_66511488	1.654	NM_001004439	ITGA11	integrin, alpha 11
chr6_-_132314004	1.651	NM_001901	CTGF	connective tissue growth factor
chr20_-_31737731	1.650		E2F1	E2F transcription factor 1
chr6_+_1336077	1.644
chr17_+_56832492	1.637		TBX2	T-box 2
chr3_+_189354167	1.637	NM_001167672	LPP	LIM domain containing preferred translocation partner in lipoma
chr10_-_71575953	1.633		TYSND1	trypsin domain containing 1
chr21_-_27139143	1.631		ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr20_+_1822943	1.627		SIRPA	signal-regulatory protein alpha
chr2_-_165186064	1.627		GRB14	growth factor receptor-bound protein 14
chr6_+_1257674	1.626	NM_033260	FOXQ1	forkhead box Q1
chr20_-_24986501	1.625		ACSS1	acyl-CoA synthetase short-chain family member 1
chr20_-_49818268	1.624		ATP9A	ATPase, class II, type 9A
chr2_-_197165495	1.623	NM_020760	HECW2	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr20_+_1822779	1.623	NM_001040022	SIRPA	signal-regulatory protein alpha
chr9_-_119217147	1.611		ASTN2	astrotactin 2
chr20_+_34635362	1.608	NM_021809	TGIF2	TGFB-induced factor homeobox 2
chr1_-_112333192	1.607	NM_004980 NM_172198	KCND3	potassium voltage-gated channel, Shal-related subfamily, member 3

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.08	4.41e-25	GO:0009987	cellular process
1.27	2.76e-15	GO:0007399	nervous system development
1.14	1.60e-14	GO:0044260	cellular macromolecule metabolic process
1.10	2.34e-14	GO:0050794	regulation of cellular process
1.09	6.56e-13	GO:0050789	regulation of biological process
1.09	1.08e-12	GO:0065007	biological regulation
1.16	1.32e-12	GO:0016043	cellular component organization
1.15	1.43e-12	GO:0071840	cellular component organization or biogenesis
1.33	3.86e-12	GO:0048699	generation of neurons
1.31	9.83e-12	GO:0022008	neurogenesis
1.14	1.68e-11	GO:0032502	developmental process
1.10	2.32e-11	GO:0044237	cellular metabolic process
1.17	5.72e-11	GO:0071841	cellular component organization or biogenesis at cellular level
1.17	1.82e-10	GO:0071842	cellular component organization at cellular level
1.11	5.39e-10	GO:0043170	macromolecule metabolic process
1.14	6.14e-10	GO:0007275	multicellular organismal development
1.16	7.07e-10	GO:0048731	system development
1.15	7.49e-10	GO:0048856	anatomical structure development
1.22	9.59e-10	GO:0009653	anatomical structure morphogenesis
1.29	1.05e-09	GO:0048468	cell development
1.32	3.54e-09	GO:0030182	neuron differentiation
1.13	1.59e-08	GO:0031323	regulation of cellular metabolic process
1.09	1.70e-08	GO:0044238	primary metabolic process
1.17	4.82e-08	GO:0048523	negative regulation of cellular process
1.12	7.08e-08	GO:0019222	regulation of metabolic process
1.12	1.75e-07	GO:0080090	regulation of primary metabolic process
1.08	2.00e-07	GO:0008152	metabolic process
1.17	5.03e-07	GO:0030154	cell differentiation
1.15	6.75e-07	GO:0044267	cellular protein metabolic process
1.32	7.40e-07	GO:0048666	neuron development
1.16	1.04e-06	GO:0048869	cellular developmental process
1.15	1.35e-06	GO:0048519	negative regulation of biological process
1.30	1.73e-06	GO:0030030	cell projection organization
1.18	2.51e-06	GO:0023051	regulation of signaling
1.33	2.67e-06	GO:0031175	neuron projection development
1.53	4.10e-06	GO:0035239	tube morphogenesis
1.29	5.08e-06	GO:0032989	cellular component morphogenesis
1.47	8.08e-06	GO:0002009	morphogenesis of an epithelium
1.17	8.17e-06	GO:0006996	organelle organization
1.19	1.11e-05	GO:0009966	regulation of signal transduction
1.27	1.25e-05	GO:0045595	regulation of cell differentiation
1.23	1.27e-05	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.11	1.33e-05	GO:0060255	regulation of macromolecule metabolic process
1.40	1.61e-05	GO:0048729	tissue morphogenesis
1.14	2.14e-05	GO:0048522	positive regulation of cellular process
1.28	2.58e-05	GO:0009887	organ morphogenesis
1.41	3.52e-05	GO:0035295	tube development
1.31	3.70e-05	GO:0000904	cell morphogenesis involved in differentiation
1.28	4.34e-05	GO:0000902	cell morphogenesis
1.22	5.58e-05	GO:0050793	regulation of developmental process
1.19	6.79e-05	GO:0009893	positive regulation of metabolic process
1.54	6.86e-05	GO:0060562	epithelial tube morphogenesis
1.19	7.05e-05	GO:0031325	positive regulation of cellular metabolic process
1.15	7.10e-05	GO:0010467	gene expression
1.12	1.18e-04	GO:0051171	regulation of nitrogen compound metabolic process
1.36	1.29e-04	GO:0007411	axon guidance
1.09	1.40e-04	GO:0051716	cellular response to stimulus
1.31	1.45e-04	GO:0048812	neuron projection morphogenesis
1.12	1.74e-04	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.15	1.75e-04	GO:0006464	protein modification process
1.10	2.15e-04	GO:0023052	signaling
1.24	2.33e-04	GO:2000026	regulation of multicellular organismal development
1.14	2.55e-04	GO:0043412	macromolecule modification
1.13	2.76e-04	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.29	3.17e-04	GO:0032990	cell part morphogenesis
1.29	3.20e-04	GO:0048858	cell projection morphogenesis
1.31	3.35e-04	GO:0048667	cell morphogenesis involved in neuron differentiation
1.21	4.23e-04	GO:0010605	negative regulation of macromolecule metabolic process
1.20	4.30e-04	GO:0009892	negative regulation of metabolic process
1.18	4.62e-04	GO:0010604	positive regulation of macromolecule metabolic process
1.24	5.01e-04	GO:0009890	negative regulation of biosynthetic process
1.12	5.32e-04	GO:0010556	regulation of macromolecule biosynthetic process
1.29	5.65e-04	GO:0072358	cardiovascular system development
1.29	5.65e-04	GO:0072359	circulatory system development
1.11	5.70e-04	GO:0019538	protein metabolic process
1.31	5.81e-04	GO:0007409	axonogenesis
1.12	6.10e-04	GO:0048518	positive regulation of biological process
1.25	6.28e-04	GO:0010558	negative regulation of macromolecule biosynthetic process
1.21	6.76e-04	GO:0031324	negative regulation of cellular metabolic process
1.10	9.40e-04	GO:0007165	signal transduction
1.11	9.50e-04	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.11	1.01e-03	GO:0009889	regulation of biosynthetic process
1.13	1.09e-03	GO:0090304	nucleic acid metabolic process
1.34	1.09e-03	GO:0060284	regulation of cell development
1.10	1.25e-03	GO:0051179	localization
1.43	1.27e-03	GO:0045664	regulation of neuron differentiation
1.13	1.46e-03	GO:0006355	regulation of transcription, DNA-dependent
1.11	1.49e-03	GO:0031326	regulation of cellular biosynthetic process
1.90	1.57e-03	GO:0035050	embryonic heart tube development
1.26	2.15e-03	GO:0045892	negative regulation of transcription, DNA-dependent
1.17	2.16e-03	GO:0051239	regulation of multicellular organismal process
1.23	2.47e-03	GO:0031327	negative regulation of cellular biosynthetic process
1.24	2.68e-03	GO:0051726	regulation of cell cycle
1.24	2.78e-03	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.26	2.99e-03	GO:0007417	central nervous system development
1.24	3.10e-03	GO:0010629	negative regulation of gene expression
1.12	3.22e-03	GO:0044249	cellular biosynthetic process
1.25	3.28e-03	GO:0051253	negative regulation of RNA metabolic process
1.14	3.43e-03	GO:0034645	cellular macromolecule biosynthetic process
1.24	3.43e-03	GO:0045893	positive regulation of transcription, DNA-dependent
1.27	3.47e-03	GO:0048646	anatomical structure formation involved in morphogenesis
1.20	3.60e-03	GO:0006351	transcription, DNA-dependent
1.10	4.01e-03	GO:0006807	nitrogen compound metabolic process
1.10	5.09e-03	GO:0034641	cellular nitrogen compound metabolic process
1.30	5.23e-03	GO:0051056	regulation of small GTPase mediated signal transduction
1.14	5.89e-03	GO:0016070	RNA metabolic process
1.25	5.93e-03	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.12	6.09e-03	GO:0051252	regulation of RNA metabolic process
1.23	6.74e-03	GO:0051172	negative regulation of nitrogen compound metabolic process
1.22	6.81e-03	GO:0007167	enzyme linked receptor protein signaling pathway
1.17	7.59e-03	GO:0010646	regulation of cell communication
1.27	7.88e-03	GO:0032583	regulation of gene-specific transcription
1.23	8.73e-03	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22	1.06e-02	GO:0010628	positive regulation of gene expression
1.11	1.32e-02	GO:0009058	biosynthetic process
1.17	1.38e-02	GO:0006793	phosphorus metabolic process
1.17	1.38e-02	GO:0006796	phosphate metabolic process
1.34	1.39e-02	GO:0001568	blood vessel development
1.13	1.41e-02	GO:0009059	macromolecule biosynthetic process
1.55	1.51e-02	GO:0003007	heart morphogenesis
1.29	1.52e-02	GO:0048598	embryonic morphogenesis
1.10	1.68e-02	GO:0010468	regulation of gene expression
1.34	1.75e-02	GO:0030036	actin cytoskeleton organization
1.32	2.00e-02	GO:0001944	vasculature development
1.24	2.01e-02	GO:0007010	cytoskeleton organization
1.44	2.18e-02	GO:0045165	cell fate commitment
1.21	2.43e-02	GO:0051254	positive regulation of RNA metabolic process
1.20	2.43e-02	GO:0010557	positive regulation of macromolecule biosynthetic process
1.28	2.57e-02	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.31	2.68e-02	GO:0030029	actin filament-based process
1.18	2.83e-02	GO:0009888	tissue development
1.47	2.88e-02	GO:0001763	morphogenesis of a branching structure
1.19	3.15e-02	GO:0051173	positive regulation of nitrogen compound metabolic process
1.34	3.19e-02	GO:0050767	regulation of neurogenesis
1.17	3.35e-02	GO:0042127	regulation of cell proliferation
1.14	3.55e-02	GO:0065009	regulation of molecular function
1.14	3.87e-02	GO:0035556	intracellular signal transduction
1.27	4.13e-02	GO:0060429	epithelium development
1.28	4.55e-02	GO:0009894	regulation of catabolic process
1.39	4.86e-02	GO:0030900	forebrain development
1.17	4.95e-02	GO:0032774	RNA biosynthetic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.08	4.16e-29	GO:0005622	intracellular
1.08	8.15e-28	GO:0044424	intracellular part
1.08	6.58e-22	GO:0043226	organelle
1.08	1.76e-21	GO:0043229	intracellular organelle
1.09	4.38e-21	GO:0043227	membrane-bounded organelle
1.09	1.56e-20	GO:0043231	intracellular membrane-bounded organelle
1.09	1.82e-19	GO:0005737	cytoplasm
1.21	1.47e-14	GO:0044428	nuclear part
1.11	1.52e-14	GO:0005634	nucleus
1.11	6.05e-13	GO:0044422	organelle part
1.11	6.54e-13	GO:0044446	intracellular organelle part
1.20	2.13e-11	GO:0031981	nuclear lumen
1.17	3.35e-10	GO:0070013	intracellular organelle lumen
1.16	1.27e-09	GO:0031974	membrane-enclosed lumen
1.16	3.05e-09	GO:0043233	organelle lumen
1.09	3.63e-09	GO:0044444	cytoplasmic part
1.02	4.69e-06	GO:0005623	cell
1.02	5.49e-06	GO:0044464	cell part
1.18	5.50e-06	GO:0005654	nucleoplasm
1.45	9.40e-05	GO:0031252	cell leading edge
1.12	5.38e-04	GO:0005829	cytosol
1.28	9.13e-04	GO:0043005	neuron projection
1.09	2.04e-03	GO:0032991	macromolecular complex
1.09	2.46e-03	GO:0043234	protein complex
1.10	3.23e-03	GO:0043228	non-membrane-bounded organelle
1.10	3.23e-03	GO:0043232	intracellular non-membrane-bounded organelle
1.19	4.58e-03	GO:0044451	nucleoplasm part
1.16	1.88e-02	GO:0042995	cell projection
1.51	1.88e-02	GO:0016585	chromatin remodeling complex
1.12	2.33e-02	GO:0012505	endomembrane system
1.19	2.48e-02	GO:0030054	cell junction
1.10	2.53e-02	GO:0031090	organelle membrane
1.27	4.09e-02	GO:0015629	actin cytoskeleton

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.13	9.54e-29	GO:0005515	protein binding
1.06	1.33e-18	GO:0005488	binding
1.24	7.79e-08	GO:0001071	nucleic acid binding transcription factor activity
1.24	7.79e-08	GO:0003700	sequence-specific DNA binding transcription factor activity
1.23	1.66e-07	GO:0030528	transcription regulator activity
1.27	3.11e-06	GO:0043565	sequence-specific DNA binding
1.30	2.40e-05	GO:0060589	nucleoside-triphosphatase regulator activity
1.30	2.40e-05	GO:0030695	GTPase regulator activity
1.30	5.49e-05	GO:0019904	protein domain specific binding
1.12	5.76e-04	GO:0000166	nucleotide binding
1.13	1.82e-03	GO:0017076	purine nucleotide binding
1.20	2.43e-03	GO:0019899	enzyme binding
1.20	2.69e-03	GO:0016301	kinase activity
1.20	2.87e-03	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.22	3.13e-03	GO:0004672	protein kinase activity
1.12	4.17e-03	GO:0032553	ribonucleotide binding
1.12	4.17e-03	GO:0032555	purine ribonucleotide binding
1.26	4.32e-03	GO:0004674	protein serine/threonine kinase activity
1.79	5.31e-03	GO:0008013	beta-catenin binding
1.30	5.84e-03	GO:0016563	transcription activator activity
1.12	7.87e-03	GO:0035639	purine ribonucleoside triphosphate binding
1.17	1.02e-02	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.13	1.53e-02	GO:0030554	adenyl nucleotide binding
1.10	1.95e-02	GO:0003677	DNA binding
1.29	2.28e-02	GO:0005083	small GTPase regulator activity
1.12	3.41e-02	GO:0032559	adenyl ribonucleotide binding
1.11	4.86e-02	GO:0016740	transferase activity